Prazosin in hypertension - two years followup of 100 cases.

One hundred cases of hypertension were investigated and treated with Prazosin alone, Prazosin with a diuretic and Prazosin, Diuretic and a Beta-adrenergic blocker. They were followed up for two and more than two years. Prazosin was found to be very safe and effective antihypertensive drug either alone or in combination with a Diuretic, or Beta-adrcnergic blocker in various grades of hypertension. Average fall of blood pressure on standing was 32.92 systolic and 22.27 diastolic. Side effects were mild and only five patients had to stop taking their drug. Prazosin was specially found quite safe antihvpertensive drug in hypertension with uraemia (JPMA 32:135, 1982).